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Observation by fluorescence microscopy of transcription on single combed DNA
Molecular combing is a powerful procedure for aligning a large array of DNA molecules onto a surface. This technique usually leads to an overstretching of about 150% of the molecules' contour length. By changing the magnitude of capillary forces during the combing process, we were able to reduc...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122892/ https://ncbi.nlm.nih.gov/pubmed/11983896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092561399 |
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