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Observation by fluorescence microscopy of transcription on single combed DNA

Molecular combing is a powerful procedure for aligning a large array of DNA molecules onto a surface. This technique usually leads to an overstretching of about 150% of the molecules' contour length. By changing the magnitude of capillary forces during the combing process, we were able to reduc...

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Detalhes bibliográficos
Main Authors: Gueroui, Z., Place, C., Freyssingeas, E., Berge, B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122892/
https://ncbi.nlm.nih.gov/pubmed/11983896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092561399
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