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Kinesin–microtubule binding depends on both nucleotide state and loading direction

Kinesin is a motor protein that transports organelles along a microtubule toward its plus end by using the energy of ATP hydrolysis. To clarify the nucleotide-dependent binding mode, we measured the unbinding force for one-headed kinesin heterodimers in addition to conventional two-headed kinesin ho...

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Detalhes bibliográficos
Main Authors: Uemura, Sotaro, Kawaguchi, Kenji, Yajima, Junichiro, Edamatsu, Masaki, Toyoshima, Yoko Yano, Ishiwata, Shin'ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122887/
https://ncbi.nlm.nih.gov/pubmed/11959922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092546199
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