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Requirement of Ca(2+) and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ
In response to IFN-γ, the latent cytoplasmic protein signal transducers and activators of transcription 1 (Stat1) becomes phosphorylated on Y701, dimerizes, and accumulates in the nucleus to activate transcription of IFN-γ-responsive genes. For maximal gene activation, S727 in the transcription acti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122886/ https://ncbi.nlm.nih.gov/pubmed/11972023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052159099 |
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