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Mission CaMKIIγ: Shuttle Calmodulin from Membrane to Nucleus
Neuronal plasticity depends on plasma membrane Ca(2+) influx, resulting in activity-dependent gene transcription. Calmodulin (CaM) activated by Ca(2+) initiates the nuclear events, but how CaM makes its way to the nucleus has remained elusive. Ma et al. now show that CaMKIIγ transports CaM from cell...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7031110/ https://ncbi.nlm.nih.gov/pubmed/25303520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.023 |
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