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Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

The recognition of MHC–peptide complexes by T cells is governed by structural considerations that are determined by the sequences of the individual components and their interaction with each other. We have studied the function of a highly diabetogenic CD8 T cell clone that is specific for insulin B1...

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Detalles Bibliográficos
Main Authors: Wong, F. Susan, Moustakas, Antonis K., Wen, Li, Papadopoulos, George K., Janeway, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC122807/
https://ncbi.nlm.nih.gov/pubmed/11943852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072037299
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