Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α

Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators. We report the solution structure of the cysteine/histidine-rich 1 (CH1) domain of p300 bound to the C-terminal transac...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Freedman, Steven J., Sun, Zhen-Yu J., Poy, Florence, Kung, Andrew L., Livingston, David M., Wagner, Gerhard, Eck, Michael J.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2002
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082117899
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