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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α

Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators. We report the solution structure of the cysteine/histidine-rich 1 (CH1) domain of p300 bound to the C-terminal transac...

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Autori principali: Freedman, Steven J., Sun, Zhen-Yu J., Poy, Florence, Kung, Andrew L., Livingston, David M., Wagner, Gerhard, Eck, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122775/
https://ncbi.nlm.nih.gov/pubmed/11959990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082117899
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