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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α
Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators. We report the solution structure of the cysteine/histidine-rich 1 (CH1) domain of p300 bound to the C-terminal transac...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122775/ https://ncbi.nlm.nih.gov/pubmed/11959990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082117899 |
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