Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension

Evidence is emerging that mechanical stretching can alter the functional states of proteins. Fibronectin (Fn) is a large, extracellular matrix protein that is assembled by cells into elastic fibrils and subjected to contractile forces. Assembly into fibrils coincides with expression of biological re...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Baneyx, Gretchen, Baugh, Loren, Vogel, Viola
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072650799
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