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Effects of 5′ Regulatory-Region Polymorphisms on Paraoxonase-Gene (PON1) Expression

Human HDL-associated paraoxonase (PON1) hydrolyzes a number of toxic organophosphorous compounds and reduces oxidation of LDLs and HDLs. These properties of PON1 account for its ability to protect against pesticide poisonings and atherosclerosis. PON1 also hydrolyzes a number of lactone and cyclic-c...

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Autors principals: Brophy, Victoria H., Jampsa, Rachel L., Clendenning, James B., McKinstry, Laura A., Jarvik, Gail P., Furlong, Clement E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226129/
https://ncbi.nlm.nih.gov/pubmed/11335891
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