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The Frequency of Hereditary Defective Mismatch Repair in a Prospective Series of Unselected Colorectal Carcinomas

A comprehensive analysis of somatic and germline mutations related to DNA mismatch–repair (MMR) genes can clarify the prevalence and mechanism of inactivation in colorectal carcinoma (CRC). In the present study, 257 unselected patients referred for CRC resection were examined for evidence of defecti...

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書誌詳細
主要な著者: Cunningham, Julie M., Kim, Cheong-Yong, Christensen, Eric R., Tester, David J., Parc, Yann, Burgart, Lawrence J., Halling, Kevin C., McDonnell, Shannon K., Schaid, Daniel J., Walsh Vockley, Catherine, Kubly, Vickie, Nelson, Heidi, Michels, Virginia V., Thibodeau, Stephen N.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society of Human Genetics 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226064/
https://ncbi.nlm.nih.gov/pubmed/11524701
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