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DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination
DNA-dependent protein kinase (DNA-PK), composed of Ku70, Ku80, and the catalytic subunit (DNA-PKcs), is involved in repairing double-strand breaks (DSBs) by nonhomologous end-joining (NHEJ). Certain proteins involved in NHEJ are also involved in DSB repair by homologous recombination (HR). To test t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122597/ https://ncbi.nlm.nih.gov/pubmed/11904432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052545899 |
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