Stop codons preceded by rare arginine codons are efficient determinants of SsrA tagging in Escherichia coli
The SsrA or tmRNA quality control system intervenes when ribosomes stall on mRNAs and directs the addition of a C-terminal peptide tag that targets the modified polypeptide for degradation. Although hundreds of SsrA-tagged proteins can be detected in cells when degradation is prevented, most of thes...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11891313/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052707199 |
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