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Stop codons preceded by rare arginine codons are efficient determinants of SsrA tagging in Escherichia coli

The SsrA or tmRNA quality control system intervenes when ribosomes stall on mRNAs and directs the addition of a C-terminal peptide tag that targets the modified polypeptide for degradation. Although hundreds of SsrA-tagged proteins can be detected in cells when degradation is prevented, most of thes...

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Hlavní autoři: Hayes, Christopher S., Bose, Baundauna, Sauer, Robert T.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122542/
https://ncbi.nlm.nih.gov/pubmed/11891313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052707199
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