Improved technique for studying ion channels expressed in Xenopus oocytes, including fast superfusion.

The study of whole-cell currents from ion channels expressed in Xenopus oocytes with conventional two-electrode voltage clamp has two major limitations. First, the large diameter and spherical geometry of oocytes prevent extremely fast solution changes. Second, the internal medium is not controlled,...

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Bibliographic Details
Main Authors: Costa, A C, Patrick, J W, Dani, J A
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225371/
https://ncbi.nlm.nih.gov/pubmed/7522597
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