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Free-energy determinants of alpha-helix insertion into lipid bilayers.

A detailed treatment is provided of the various free-energy terms that contribute to the transfer of a polyalanine alpha-helix from the aqueous phase into lipid bilayers. In agreement with previous work, the hydrophobic effect is found to provide the major driving force for helix insertion. However,...

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Detalhes bibliográficos
Main Authors: Ben-Tal, N, Ben-Shaul, A, Nicholls, A, Honig, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225150/
https://ncbi.nlm.nih.gov/pubmed/8785340
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