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Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor.

A 12-kDa immunophilin (FKBP12) is an integral component of the skeletal muscle ryanodine receptor (RyR). The RyR is a hetero-oligomeric complex with structural formula (FKBP)4(Ryr1)4, where Ryr1 is the 565-kDa product of the Ryr1 gene. To aid in the detection of the immunophilin's location in t...

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Main Authors: Wagenknecht, T, Grassucci, R, Berkowitz, J, Wiederrecht, G J, Xin, H B, Fleischer, S
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225139/
https://ncbi.nlm.nih.gov/pubmed/8785329
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