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Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac)

Fluoxetine (Prozac) is the most widely prescribed medication for the treatment of depression. Nevertheless, little is known about the molecular basis of its clinical efficacy, apart from the fact that fluoxetine increases the synaptic availability of serotonin. Here we show that, in vivo, fluoxetine...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Svenningsson, Per, Tzavara, Eleni T., Witkin, Jeffrey M., Fienberg, Allen A., Nomikos, George G., Greengard, Paul
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11880651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052712799
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