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Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events.

We present here a maximal likelihood algorithm for estimating single-channel kinetic parameters from idealized patch-clamp data. The algorithm takes into account missed events caused by limited time resolution of the recording system. Assuming a fixed dead time, we derive an explicit expression for...

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Detalhes bibliográficos
Main Authors: Qin, F, Auerbach, A, Sachs, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224925/
https://ncbi.nlm.nih.gov/pubmed/8770203
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