Noninvasive quantitative imaging of protein–protein interactions in living subjects

We are developing methods to image molecular and cellular events in living subjects. In this study, we validate imaging of protein—protein interactions in living mice by using bioluminescent optical imaging. We use the well studied yeast two-hybrid system adapted for mammalian cells and modify it to...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Ray, P., Pimenta, H., Paulmurugan, R., Berger, F., Phelps, M. E., Iyer, M., Gambhir, S. S.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2002
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122480/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052710999
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