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Noninvasive quantitative imaging of protein–protein interactions in living subjects

We are developing methods to image molecular and cellular events in living subjects. In this study, we validate imaging of protein—protein interactions in living mice by using bioluminescent optical imaging. We use the well studied yeast two-hybrid system adapted for mammalian cells and modify it to...

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Detalhes bibliográficos
Main Authors: Ray, P., Pimenta, H., Paulmurugan, R., Berger, F., Phelps, M. E., Iyer, M., Gambhir, S. S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122480/
https://ncbi.nlm.nih.gov/pubmed/11854471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052710999
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