NQO1 stabilizes p53 through a distinct pathway

Wild-type p53 is a tumor-suppressor gene that encodes a short-lived protein that, upon accumulation, induces growth arrest or apoptosis. Accumulation of p53 occurs mainly by posttranslational events that inhibit its proteosomal degradation. We have reported previously that inhibition of NAD(P)H: qui...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Asher, Gad, Lotem, Joseph, Kama, Rachel, Sachs, Leo, Shaul, Yosef
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2002
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052706799
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