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NQO1 stabilizes p53 through a distinct pathway
Wild-type p53 is a tumor-suppressor gene that encodes a short-lived protein that, upon accumulation, induces growth arrest or apoptosis. Accumulation of p53 occurs mainly by posttranslational events that inhibit its proteosomal degradation. We have reported previously that inhibition of NAD(P)H: qui...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122479/ https://ncbi.nlm.nih.gov/pubmed/11867746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052706799 |
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