NQO1 stabilizes p53 through a distinct pathway

Wild-type p53 is a tumor-suppressor gene that encodes a short-lived protein that, upon accumulation, induces growth arrest or apoptosis. Accumulation of p53 occurs mainly by posttranslational events that inhibit its proteosomal degradation. We have reported previously that inhibition of NAD(P)H: qui...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Asher, Gad, Lotem, Joseph, Kama, Rachel, Sachs, Leo, Shaul, Yosef
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 2002
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052706799
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