Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

Despite recent treatment advances, the majority of patients with chronic hepatitis C fail to respond to antiviral therapy. Although the genetic basis for this resistance is unknown, accumulated evidence suggests that changes in the heterogeneous viral population (quasispecies) may be an important de...

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Dettagli Bibliografici
Autori principali: Farci, Patrizia, Strazzera, Rita, Alter, Harvey J., Farci, Stefania, Degioannis, Daniela, Coiana, Alessandra, Peddis, Giovanna, Usai, Francesco, Serra, Giancarlo, Chessa, Luchino, Diaz, Giacomo, Balestrieri, Angelo, Purcell, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122476/
https://ncbi.nlm.nih.gov/pubmed/11880647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052712599
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