Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

Despite recent treatment advances, the majority of patients with chronic hepatitis C fail to respond to antiviral therapy. Although the genetic basis for this resistance is unknown, accumulated evidence suggests that changes in the heterogeneous viral population (quasispecies) may be an important de...

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Bibliographic Details
Main Authors: Farci, Patrizia, Strazzera, Rita, Alter, Harvey J., Farci, Stefania, Degioannis, Daniela, Coiana, Alessandra, Peddis, Giovanna, Usai, Francesco, Serra, Giancarlo, Chessa, Luchino, Diaz, Giacomo, Balestrieri, Angelo, Purcell, Robert H.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC122476/
https://ncbi.nlm.nih.gov/pubmed/11880647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052712599
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