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Regulatory Serine Residues Mediate Phosphorylation-dependent and Phosphorylation-independent Activation of Interferon Regulatory Factor 7
Interferon regulatory factor (IRF)7 is a key transcription factor required for establishment of antiviral resistance. In response to infection, IRF7 is activated by phosphorylation through the action of the non-canonical IκB kinases, IκB kinase-ε and TANK-binding kinase 1. Activation leads to nuclea...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224706/ https://ncbi.nlm.nih.gov/pubmed/15743772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411389200 |
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