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Regulatory Serine Residues Mediate Phosphorylation-dependent and Phosphorylation-independent Activation of Interferon Regulatory Factor 7

Interferon regulatory factor (IRF)7 is a key transcription factor required for establishment of antiviral resistance. In response to infection, IRF7 is activated by phosphorylation through the action of the non-canonical IκB kinases, IκB kinase-ε and TANK-binding kinase 1. Activation leads to nuclea...

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Sonraí Bibleagrafaíochta
Main Authors: Caillaud, Alexandre, Hovanessian, Ara G., Levy, David E., Marié, Isabelle J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224706/
https://ncbi.nlm.nih.gov/pubmed/15743772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411389200
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