טוען...
Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors
For gene therapy of inherited diseases, targeted integration/gene repair through homologous recombination (HR) between exogenous and chromosomal DNA would be an ideal strategy to avoid potentially serious problems of random integration such as cellular transformation and gene silencing. Efficient se...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224662/ https://ncbi.nlm.nih.gov/pubmed/16174752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506598102 |
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