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Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules

We previously reported that an Nkx2-5-GFP bacterial artificial chromosome in transgenic mice recapitulated the endogenous gene activity in the heart. Here, we identified three additional previously uncharacterized distal enhancer modules of Nkx2-5: UH6, which directed transgene expression in the rig...

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Detalhes bibliográficos
Main Authors: Chi, Xuan, Chatterjee, Pradeep K., Wilson, Willie, Zhang, Shu-Xing, DeMayo, Franco J., Schwartz, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224629/
https://ncbi.nlm.nih.gov/pubmed/16150722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504295102
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