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Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases

Several neurodegenerative diseases are linked to expanded repeats of glutamine residues, which lead to the formation of amyloid fibrils and neuronal death. The length of the repeats correlates with the onset of Huntington's disease, such that healthy individuals have <38 residues and individ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Armen, Roger S., Bernard, Brady M., Day, Ryan, Alonso, Darwin O. V., Daggett, Valerie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224618/
https://ncbi.nlm.nih.gov/pubmed/16157882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502068102
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