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Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases
Several neurodegenerative diseases are linked to expanded repeats of glutamine residues, which lead to the formation of amyloid fibrils and neuronal death. The length of the repeats correlates with the onset of Huntington's disease, such that healthy individuals have <38 residues and individ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224618/ https://ncbi.nlm.nih.gov/pubmed/16157882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502068102 |
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