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Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control.

CARF, a collaborator of ARF (alternative reading frame protein), was cloned as a novel ARF-binding protein from a yeast-interaction screen. It potentiated ARF-mediated p53 function, and also caused a moderate increase in p53 activity in the absence of ARF. We herein report the molecular mechanism of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hasan, Md Kamrul, Yaguchi, Tomoko, Minoda, Yasumasu, Hirano, Takashi, Taira, Kazunari, Wadhwa, Renu, Kaul, Sunil C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224239/
https://ncbi.nlm.nih.gov/pubmed/15109303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040337
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