Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors.

Alpha-conotoxin GIC is a 16-residue peptide isolated from the venom of the cone snail Conus geographus. Alpha-conotoxin GIC potently blocks the alpha3beta2 subtype of human nicotinic acetylcholine receptor, showing a high selectivity for neuronal versus muscle subtype [McIntosh, Dowell, Watkins, Gar...

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Détails bibliographiques
Auteurs principaux: Chi, Seung-Wook, Kim, Do-Hyoung, Olivera, Baldomero M, McIntosh, J Michael, Han, Kyou-Hoon
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224189/
https://ncbi.nlm.nih.gov/pubmed/14992691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031792
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