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Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity
Tissue transglutaminase (TG) is a Ca(2+)-dependent acyltransferase with roles in cellular differentiation, apoptosis, and other biological functions. In addition to being a transamidase, TG undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-b...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122418/ https://ncbi.nlm.nih.gov/pubmed/11867708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042454899 |
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