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Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex.

The assembly of a branched network of actin filaments provides the mechanical propulsion that drives a range of dynamic cellular processes, including cell motility. The Arp2/3 complex is a crucial component of such filament networks. Arp2/3 nucleates new actin filaments while bound to existing filam...

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Autori principali: Millard, Thomas H, Sharp, Stewart J, Machesky, Laura M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224166/
https://ncbi.nlm.nih.gov/pubmed/15040784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040176
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