Nucleotides and phospholipids compete for binding to the C terminus of K(ATP) channels

Inwardly rectifying, ATP-sensitive K(+) channels (K(ATP)) couple metabolism to either cell excitability (Kir6.x) or potassium secretion (Kir1.1). Phosphatidylinositol phospholipids, like PI(4,5)P(2), antagonize nucleotide inhibition of K(ATP) channels enhancing the coupling of metabolic events to ce...

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Bibliografiske detaljer
Main Authors: MacGregor, Gordon G., Dong, Ke, Vanoye, Carlos G., Tang, LieQi, Giebisch, Gerhard, Hebert, Steven C.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122415/
https://ncbi.nlm.nih.gov/pubmed/11880626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042688899
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