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Nucleotides and phospholipids compete for binding to the C terminus of K(ATP) channels

Inwardly rectifying, ATP-sensitive K(+) channels (K(ATP)) couple metabolism to either cell excitability (Kir6.x) or potassium secretion (Kir1.1). Phosphatidylinositol phospholipids, like PI(4,5)P(2), antagonize nucleotide inhibition of K(ATP) channels enhancing the coupling of metabolic events to ce...

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Detalhes bibliográficos
Main Authors: MacGregor, Gordon G., Dong, Ke, Vanoye, Carlos G., Tang, LieQi, Giebisch, Gerhard, Hebert, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122415/
https://ncbi.nlm.nih.gov/pubmed/11880626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042688899
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