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Cell-cycle-dependent translation of histone mRNAs is the key control point for regulation of histone biosynthesis in Leishmania infantum.

The cell-cycle-dependent expression of the four core histones (H2A, H2B, H3 and H4) has been studied in the protozoan parasite Leishmania infantum. For that purpose, the cell cycle was arrested by incubation of promastigotes with the DNA synthesis inhibitor hydroxyurea, which induced an accumulation...

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Detalhes bibliográficos
Main Authors: Soto, Manuel, Iborra, Salvador, Quijada, Luis, Folgueira, Cristina, Alonso, Carlos, Requena, Jose M
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224130/
https://ncbi.nlm.nih.gov/pubmed/14766017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031522
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