A combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin.

The black pigment of Porphyromonas gingivalis is composed of the mu-oxo bishaem complex of Fe(III) protoporphyrin IX (mu-oxo oligomer, dimeric haem), namely [Fe(III)PPIX]2O. P. gingivalis W50 and Rgp (Arg-gingipain)- and Kgp (Lys-gingipain)-deficient mutants K1A, D7, E8 and W501 [Aduse-Opoku, Davies...

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Bibliografiska uppgifter
Huvudupphovsmän: Smalley, John W, Thomas, Michael F, Birss, Andrew J, Withnall, Robert, Silver, Jack
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224116/
https://ncbi.nlm.nih.gov/pubmed/14741050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031221
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