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Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail.

Integrin cytoplasmic tails regulate integrin activation including an increase in integrin affinity for ligands. Although there is ample evidence that the membrane-proximal regions of the alpha and beta tails interact with each other to maintain integrins in a low-affinity state, little is known abou...

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Détails bibliographiques
Auteurs principaux: Yamanouchi, Jun, Hato, Takaaki, Tamura, Tatsushiro, Fujita, Shigeru
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224082/
https://ncbi.nlm.nih.gov/pubmed/14723599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031753
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