Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester.

PAPP-A (pregnancy-associated plasma protein-A) is produced by hSFs (human skin fibroblasts) and hOBs (human osteoblasts) and enhances the mitogenic activity of IGFs (insulin-like growth factors) by degradation of IGFBP-4 (insulin-like growth factor-binding protein 4). PKC (protein kinase C) activati...

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Detalhes bibliográficos
Main Authors: Sivanandam, Arun S, Mohan, Subburaman, Kita, Hirohito, Kapur, Sanjay, Chen, Shin-Tai, Linkhart, Thomas A, Bagi, Gyorgy, Baylink, David J, Qin, Xuezhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224057/
https://ncbi.nlm.nih.gov/pubmed/14705967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030937
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