N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase.

Anandamide ( N-arachidonoylethanolamine) and other bioactive N-acylethanolamines are degraded to their corresponding fatty acids and ethanolamine. This hydrolysis is mostly attributed to catalysis by FAAH (fatty acid amide hydrolase), which exhibits an alkaline pH optimum. In addition, we have ident...

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Autori principali: Tsuboi, Kazuhito, Hilligsmann, Christine, Vandevoorde, Séverine, Lambert, Didier M, Ueda, Natsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224050/
https://ncbi.nlm.nih.gov/pubmed/14686878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031695
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