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Phosphoinositides differentially regulate alpha-actinin flexibility and function.

Alpha-actinin is a cell-adhesion and cytoskeletal protein that bundles actin microfilaments and links these filaments directly to integrin-adhesion receptors. Phosphoinositides bind to and regulate the interaction of a-actinin with actin filaments and integrin receptors. In the present study, we dem...

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Autors principals: Corgan, Anne Marie, Singleton, CoreyAyne, Santoso, Cynthia B, Greenwood, Jeffrey A
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224031/
https://ncbi.nlm.nih.gov/pubmed/14670080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031124
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