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A synergistic relationship between three regions of stathmin family proteins is required for the formation of a stable complex with tubulin.

Stathmin is a ubiquitous 17 kDa cytosolic phosphoprotein proposed to play a general role in the integration and relay of intracellular signalling pathways. It is believed to regulate microtubule dynamics by sequestering tubulin in a complex made of two tubulin heterodimers per stathmin molecule (T2S...

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Detalhes bibliográficos
Main Authors: Jourdain, Isabelle, Lachkar, Sylvie, Charbaut, Elodie, Gigant, Benoit, Knossow, Marcel, Sobel, André, Curmi, Patrick A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224029/
https://ncbi.nlm.nih.gov/pubmed/14670078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031413
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