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Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.

Cysteine proteases play important roles in the life cycles of malaria parasites. Cysteine protease inhibitors block haemoglobin hydrolysis and development in Plasmodium falciparum, suggesting that the cysteine proteases of this major human pathogen, termed falcipains, are appropriate therapeutic tar...

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Bibliografiske detaljer
Main Authors: Na, Byoung-Kuk, Shenai, Bhaskar R, Sijwali, Puran S, Choe, Youngchool, Pandey, Kailash C, Singh, Ajay, Craik, Charles S, Rosenthal, Philip J
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223978/
https://ncbi.nlm.nih.gov/pubmed/14629194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031487
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