Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.

Cysteine proteases play important roles in the life cycles of malaria parasites. Cysteine protease inhibitors block haemoglobin hydrolysis and development in Plasmodium falciparum, suggesting that the cysteine proteases of this major human pathogen, termed falcipains, are appropriate therapeutic tar...

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Библиографические подробности
Главные авторы: Na, Byoung-Kuk, Shenai, Bhaskar R, Sijwali, Puran S, Choe, Youngchool, Pandey, Kailash C, Singh, Ajay, Craik, Charles S, Rosenthal, Philip J
Формат: Artigo
Язык:Inglês
Опубликовано: 2004
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223978/
https://ncbi.nlm.nih.gov/pubmed/14629194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031487
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