Llwytho...

The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIa.

The seven-amino-acid peptide LSARLAF has been reported to activate platelets via the integrin GPIIb-IIIa (glycoprotein IIb-IIIa). Activation by LSARLAF is reinforced by release of ADP and thromboxanes, but the initiating event in the signalling cascade is not known. In the present study, we demonstr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pearce, Andrew C, Wonerow, Peter, Marshall, Stuart J, Frampton, Jon, Gartner, T Kent, Watson, Steve P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223919/
https://ncbi.nlm.nih.gov/pubmed/14558887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031298
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