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Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons.

The human mitochondrial genome (mtDNA) is a small, circular DNA duplex found in multi-copy in the mitochondrial matrix. It is almost fully transcribed from both strands to produce large polycistronic RNA units that are processed and matured. The 13 mtDNA-encoded polypeptides are translated from mt-m...

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Autori principali: Chrzanowska-Lightowlers, Zofia M A, Temperley, Richard J, Smith, Paul M, Seneca, Sara H, Lightowlers, Robert N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223913/
https://ncbi.nlm.nih.gov/pubmed/14585098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031556
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