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Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms.
The sensitivity of Coxs (cyclo-oxygenases) to inhibition is known to be highly dependent on assay conditions. In the present study, the inhibitor sensitivities of purified Cox-1 and -2 were determined in a colorimetric assay using the reducing agent N, N, N ', N '-tetramethyl- p -phenylene...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223887/ https://ncbi.nlm.nih.gov/pubmed/14510637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030969 |
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