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Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells.

Abrin belongs to the type II family of ribosome-inactivating proteins comprising a galactose-binding B chain coupled with a toxic A chain through a single disulphide linkage. Apart from its RNA-N-glycosidase activity, another role that has been recently ascribed to abrin was the induction of apoptos...

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Detalhes bibliográficos
Main Authors: Narayanan, Sriram, Surolia, Avadhesha, Karande, Anjali A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223838/
https://ncbi.nlm.nih.gov/pubmed/13129434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030797
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