Coagulation factor Va Glu-96-Asp-111: a chelator-sensitive site involved in function and subunit association.

Coagulation FVa (factor Va) accelerates the essential generation of thrombin by FXa (factor Xa). Although the noncovalent Ca2+-dependent association between the FVa light and heavy subunits (FVaL and FVaH) is required for function, little is known about the specific residues involved. Previous fragm...

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Hlavní autoři: Zeibdawi, Abed R, Grundy, Jean E, Lasia, Bogna, Pryzdial, Edward L G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223830/
https://ncbi.nlm.nih.gov/pubmed/12948396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031205
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