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Coagulation factor Va Glu-96-Asp-111: a chelator-sensitive site involved in function and subunit association.
Coagulation FVa (factor Va) accelerates the essential generation of thrombin by FXa (factor Xa). Although the noncovalent Ca2+-dependent association between the FVa light and heavy subunits (FVaL and FVaH) is required for function, little is known about the specific residues involved. Previous fragm...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223830/ https://ncbi.nlm.nih.gov/pubmed/12948396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031205 |
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