Chargement en cours...
Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
EGF (epidermal growth factor) binding to its receptor (EGFR) induces dimerization and autophosphorylation of the receptor at multiple tyrosine residues, which serve as docking sites for recruitment of proteins with SH2 (Src homology 2) domains that activate multiple downstream signalling pathways. T...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2003
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223792/ https://ncbi.nlm.nih.gov/pubmed/14498832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030668 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|